Beta-lactamase production by Escherichia coli under different growth conditions

Saverino, D.

New Microbiologica 25(1): 89-91

2002


ISSN/ISBN: 1121-7138
PMID: 11837396
Document Number: 548062
Facultative anaerobic bacteria, such as Escherichia coli, are more resistant to cephalosporin antibiotics during anaerobic growth. Strict anaerobic ambience reduces beta-lactamase production or the enzyme affinities for their substrates. A different balance between DNA gyrase and topoisomerase I activity, during aerobic and anaerobic growth condition, could be related to the bacteria behavior.

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