Beta-lactamase production by Escherichia coli under different growth conditions
Saverino, D.
New Microbiologica 25(1): 89-91
2002
ISSN/ISBN: 1121-7138 PMID: 11837396 Document Number: 548062
Facultative anaerobic bacteria, such as Escherichia coli, are more resistant to cephalosporin antibiotics during anaerobic growth. Strict anaerobic ambience reduces beta-lactamase production or the enzyme affinities for their substrates. A different balance between DNA gyrase and topoisomerase I activity, during aerobic and anaerobic growth condition, could be related to the bacteria behavior.
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