Effect of GABA and pyracetam on mitochondrial ADP phosphorylation in experimental hypokinesia
Sotskiĭ, O.P.; Akopian, V.P.; Zhamgarian, L.G.; Zhamgarian, A.G.
Voprosy Meditsinskoi Khimii 48(5): 485-489
2002
ISSN/ISBN: 0042-8809 PMID: 12498091 Document Number: 547816
Long-term limitation of motor activity of male rats is accompanied by impairments of mitochondrial ADP phosphorylation in liver and heart. The most significant changes were observed after 15 and 45 days of hypokinesia. Administration of GABA and pyracetam to animals subjected to hypokinesia induced a tendency to "normalization" of ADP phosphorilation processes.
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