Prognostic value of cardiac troponin i in patients with non-ST elevation acute coronary syndrome
Korotkova, A.A.; Titov, V.N.; Staroverov, I.I.
Kardiologiia 42(4): 19-22
2002
ISSN/ISBN: 0022-9040 PMID: 12494161 Document Number: 547563
To elucidate relationship between initial blood levels of troponin I and occurrence of such events as death, myocardial infarction, coronary artery bypass surgery, and angioplasty in patients with non-ST elevation acute coronary syndrome. One hundred one patients aged 32-78 years admitted to coronary care unit within 24 hours after onset of pain including 69 (68.3%) with unstable angina and 32 (31.7%) with non-ST elevation myocardial infarction. Troponin I was determined by immunoassay, values below 0.4 ng/ml were considered normal. RESULTS. During 30 days of hospitalization there were 16 (35.5%) and 5 events (8.9%) events (p=0.001) among 45 patients who had elevated level of troponin I (group 1) and 56 patients with normal troponin I (group 2), respectively. By 6 months events occurred in 19 (42.2%) and 6 (10.7%) patients in groups 1 and 2, respectively (p=0.0004). Thus elevated blood level of troponin I in patients with non-ST elevation acute coronary syndrome has important value for prognosis.