Is buprenorphine a potential alternative to methadone for treating pregnant drug users? Inventory of clinical data in the literature
Loustauneau, A.; Auriacombe, M.; Daulouede, J-Pierre.; Tignol, J.
Annales de Medecine Interne 153(7 Suppl): 2s31-2s36
2002
ISSN/ISBN: 0003-410X PMID: 12518080 Document Number: 547418
In this review of the literature, we collected 102 case reports of newborns exposed in utero to buprenorphine between 1996 and 2000. Reported data show that infants born to a mother taking buprenorphine are delivered at term and have a birth weight close to infants not exposed to these substances. The published data also showed that observations have varied concerning the frequency, intensity, and duration of the withdrawal syndrome in newborns exposed in utero to buprenorphine.
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