A controlled trial of methadone maintenance in a population of intravenous drug users in Bangkok: implications for prevention of HIV
Vanichseni, S.; Wongsuwan, B.; Choopanya, K.; Wongpanich, K.
International Journal of the Addictions 26(12): 1313-1320
1991
ISSN/ISBN: 0020-773X PMID: 1787024 Document Number: 320090
This study represents the first controlled trial of methadone maintenance and 45-day methadone detoxification in Thailand. We randomly assigned 240 male heroin addicts with at least six prior detoxification treatment episodes to 45-day detoxification or to methadone maintenance treatment conditions. We found that methadone maintenance clients were more likely to complete 45 days of treatment (p < .00001), were less likely to have used heroin during treatment (p < .0002), and were less likely to have used heroin on the 45th day of treatment (p < .000007). These findings are consistent with the results of other studies in the United States, and we conclude that methadone maintenance could be a significant adjunct to AIDS prevention efforts for intravenous drug users in Thailand.
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