Acute interstitial nephritis caused by clozapine
Estébanez, C.; Fernández Reyes, M.J.; Sánchez Hernández, R.; Mon, C.; Rodríguez, F.; Alvarez-Ude, F.; Mampaso, F.
Nefrologia Publicacion Oficial de la Sociedad Espanola Nefrologia 22(3): 277-281
2002
ISSN/ISBN: 0211-6995 PMID: 12123128 Document Number: 547242
We are reporting a case of a 69 years old man developed acute renal failure due to interstitial nephritis during treatment with the drug clozapine, and that improve after to discontinuation of this drug. The clozapine is a new antipsychotic drug that may produce severes adverses reactions, like medullary toxicity. Recently 10 cases of clozapine-induced AIN have been reported. We want to associate to the cases publicated with a new case because it is a severe adverse reaction.