Formation and structural organization of a barrier on the brain outer surface
Otellin, V.A.; Korzhevskiĭ, D.E.
Morfologiia 122(6): 14-18
2002
ISSN/ISBN: 1026-3543 PMID: 12630086 Document Number: 546378
Using the methods of light and electron microscopy and immunocytochemistry, the barrier structures on the outer surface of the forming human brain were studied in the early prenatal period of development. The data obtained suggest that the superficial barrier in the forming brain is heteromorphous and consists of differently specialized morpho-functional complexes. The areas of contact of developing brain surface with blood capillaries of pericerebral vascular network were found to be the zone of the blood-brainbarrier formation, while the areas of the surface bordering the meningeal extracellular matrix were the zone of future liquor-brain barrier.