Changes in the ultrastructure of the stomach mucous membrane parietal cells caused by inhibitors of hydrochloric acid secretion
Dondukova, G.V.; Morozov, I.A.
Arkhiv Patologii 64(3): 16-20
2002
ISSN/ISBN: 0004-1955 PMID: 15338718 Document Number: 545332
The study of the action of phamotidine and omeprazol on the stomach parietal cells in patients with duodenal ulcer has shown that phamotidin results in changes of secretory membrane of the parietal cells increasing its secretory potential while omeprazol reduces energetic metabolism of the lining cell by the impact on its mitochondrial apparatus. Both in children and adults with duodenal ulcer more developed mitochondrial cell activity was found after omeprazol treatment.