Invitro comparative evaluation of aminoglycosides at a cancer centre
Biswas, S.K.; Kelkar, R.S.
Indian Journal of Cancer 39(4): 135-138
2002
ISSN/ISBN: 0019-509X PMID: 12928571 Document Number: 544176
A comparative study of in vitro activity of amikacin, gentamicin, netilmicin, tobramycin and isepamicin was done. A total of 200 clinical isolates of Gram negative organisms from various clinical sources were tested. E.Coli was the most frequently isolated organism followed by Pseudomonas spp., Klebsiella spp., Proteus spp., Acinetobacter spp. and Enterobacter spp. Of the 5 aminoglycosides tested, isepamicin showed the highest numbers of susceptible isolates followed by amikacin, netilmicin, gentamicin and tobramycin. MIC 90 value of isepamicin was lower as compared to amikacin.