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Comparative activity of habekacin and 4 other aminoglycosides against gram-negative bacilli. Evolution of resistance

Reynaud, A.E.; Coude du Foresto, B.; Derriennic, M.; Courtieu, A.L.

Pathologie-Biologie 36(5): 435-438

1988

ISSN/ISBN: 0369-8114
PMID: 3136424
Document Number: 305526
The activity of 5 aminoglycosides compounds (habekacin, amikacin, gentamicin, netilmicin and tobramycin) was studied by an agar dilution method, against 235 strains of Enterobacteriaceae and 146 other Gram negative bacilli. 79 to 98% of susceptible strains were observed, according to the aminoglycoside compound. Habekacin and amikacin were the most effective, specially against the more frequently resistant bacteria: Enterobacter, Serratia, Hafnia, Acinetobacter, Pseudomonas aeruginosa. In comparison with a previous study, no evolution was observed in the resistance to aminoglycosides.

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