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Human polyoma virus BK DNA detection by nested PCR in renal transplant recipients

Bergallo, M.; Merlino, C.; Bollero, C.; Scutera, S.; Sinesi, F.; Cavallo, R.

New Microbiologica 25(3): 331-334

2002

ISSN/ISBN: 1121-7138
PMID: 12173775
Document Number: 543141
Several studies report a correlation between the human polyomavirus BK (BKV) and interstitial nephritis in renal transplant recipients in whom immunosuppressive treatment is thought to allow or induce reactivation of the virus. Furthermore, it is described that nephropathy may result from the use of newly introduced immunosuppressive drugs. In the present study, we evaluated the presence of BKV DNA by nested-PCR (n-PCR) in urine and serum samples from 35 renal transplant patients related to the immunosuppressive regimens and renal function.

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