What are the arguments in favour of local allocation of kidneys harvested for transplantation?
Benoit, G.ér.; Eschwege, P.; Blanchet, P.; Droupy, S.ép.; Brivet, F.ço.; Coulomb, F.ço.; Charpentier, B.; Duranteau, J.
Progres en Urologie Journal de l'Association Francaise d'Urologie et de la Societe Francaise d'Urologie 12(3): 405-408
2002
ISSN/ISBN: 1166-7087 PMID: 12189746 Document Number: 542897
The rules of organ allocation allow one of the two kidneys harvested to be transplanted locally while the other is exchanged. This rule of local priority does not exist in all countries. The purpose of this article is to determine whether this rule provides a benefit for the patient. 804 locally harvested kidneys were compared to 1196 exchanged kidneys transplanted between 1970 and 2000 by the same renal transplantation team. The cold ischaemia time was shorter (-6 h), the number of cases of HLA identity was lower (-0.8), the rate of acute tubular necrosis was lower (-9), and the median graft survival of was 7 months longer for local kidneys. An article analysing the North American register reached similar conclusions: the local attribution rule reduces the cold ischaemia and the graft loss at one year. The local attribution rule has the advantage of increasing the organ harvesting rate from borderline donors, reducing the cold ischaemia, and improving the results: this rule should therefore be maintained.