Multiple brown tumors in a female hemodialyzed patient with severe secondary hyperparathyroidism
Peces, R.; Gil, F.; González, F.; Ablanedo, P.
Nefrologia Publicacion Oficial de la Sociedad Espanola Nefrologia 22(1): 79-82
2002
ISSN/ISBN: 0211-6995 PMID: 11987690 Document Number: 542807
Skeletal brown tumours are relatively uncommon, and brown tumours that involve multiple bones are considered very rare. We describe a 29-year-old woman with chronic renal failure (CRF) who had undergone hemodialysis for 21 years and developed multiple brown tumours associated with severe secondary hyperparathyroidism. Computed tomography (CT) revealed multiple brown tumours involving scapula, ribs, spine and sacroiliac bone. Microscopic analysis of the brown tumour showed dense infiltration of the marrow space by reactive fibroblastic tissue with irregularly distributed multinucleated osteoclastic giants cells and marked increase in hematopoietic elements.