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Investigation of beta-D-glucan values in the vitreous

Shimbo, M.; Ito, N.; Kadonosono, K.

Nippon Ganka Gakkai Zasshi 106(9): 579-582

2002

ISSN/ISBN: 0029-0203
PMID: 12385123
Document Number: 542062
Purpose: beta-D-glucan values in the vitreous were investigated in order to evaluate their usefulness for the diagnosis of fungal endophthalmitis. Methods: The vitreous or vitreous perfusate were collected from twenty-six patients who underwent vitreous surgery at the Department of Ophthalmology, Yokohama City University, School of Medicine and beta-D-glucan values in these samples were examined. Results: Two samples with fungal endophthalmitis showed remarkably high concentration beta-D-glucan values. The other samples, except one, without fungal endophthalmitis showed significantly low beta-D-glucan values of less than 10.0 pg/ml. Conclusion: It is expected that beta-D-glucan values in the vitreous may be more sensitive than culture methods, and may be useful for the diagnosis of fungal endophthalmitis.

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