Top Abstract Purchase Related
Home
>
Node
>
Subnode

Exclusion of CARD15/NOD2 as a candidate susceptibility gene to psoriasis in the Italian population

Borgiani, P.; Vallo, L.; D'Apice, M.R.; Giardina, E.; Pucci, S.; Capon, F.; Nisticò, S.; Chimenti, S.; Pallone, F.; Novelli, G.

European Journal of Dermatology Ejd 12(6): 540-542

2002

ISSN/ISBN: 1167-1122
PMID: 12459523
Document Number: 542061
Psoriasis is a chronic inflammatory skin disorder showing multifactorial inheritance. Linkage studies have mapped disease susceptibility loci to several genomic regions, including the chromosome 16 interval that contains the CARD15/NOD2 gene. CARD15 has been involved in Crohn's Disease (CD) susceptibility and it has been hypothesised that it may also contribute to the pathogenesis of psoriasis. To test this hypothesis we studied the distribution of 3 CARD15 SNPs in an Italian case-control data set. We failed to observe any significant difference between patients and controls, thereby excluding the presence of a strong genetic association between CARD15 gene polymorphisms and psoriasis, in the Italian population.

Document emailed within 1 workday
Secure & encrypted payments

Sun, Y.P. 1986: Linkage between HLA and the susceptibility gene of psoriasis Zhonghua Yi Xue Za Zhi 66(10): 600-604
Kozarova, M.; Javorsky, M.; Stancakova, A.; Dobrikova, M.; Habalova, V.; Klimcakova, L.; Zidzik, J.; Haluskova, J.; Salagovic, J.; Tkac, I. 2010: Relationship of five type 2 diabetes candidate gene polymorphisms to the age at diagnosis of diabetes in the Slovakian population Bratislavske Lekarske Listy 111(3): 150-152
Chiò, A.; Orsi, L.; Mortara, P.; Schiffer, D. 1993: Early onset cerebellar ataxia with retained tendon reflexes: prevalence and gene frequency in an Italian population Clinical Genetics 43(4): 207-211
Karahalil, B.; Kocabas, N.A.ün.; Ozçelik, T. 2006: DNA repair gene polymorphisms and bladder cancer susceptibility in a Turkish population Anticancer Research 26(6c): 4955-4958
Xu, L.; Qiao, Y.; Zhang, X.; Sun, H.; Wang, J.; Sun, D.; Jia, X.; Shen, C.; Zhao, Y.; Jin, Y.; Yu, Y.; Ling, H.; Wang, K.; Fu, S. 2011: A haplotype in the CCR5 gene promoter was associated with the susceptibility to HIV-1 infection in a northern Chinese population Molecular Biology Reports 38(1): 327-332
Skvortsova, V.I.; Slominskiĭ, P.A.; Shadrina, M.I.; Levitskiĭ, G.N.; Levitskaia, N.I.; Alekhin, A.V.; Zherebtsova, A.L.; Serdiuk, A.V.; Limborskaia, S.A. 2006: Detoxication gene polymorphism and susceptibility to sporadic motor neuron disease in Russian population Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova 106(1): 4-13
Zhao, X.; He, Y.; Zhang, T.; Wang, C.; Zhang, W.; Yu, W.; Guan, Z. 2016: Study on association between HLA-DP gene polymorphism and susceptibility to hepatitis B virus infection in minority population in Guizhou province Zhonghua Liu Xing Bing Xue Za Zhi 37(3): 389-393
Serrano, A.; Carmona, F.D.; Miranda-Filloy, J.é A.; Castañeda, S.; Rodríguez-Rodríguez, L.; Morado, I.C.; Gómez-Vaquero, C.; Solans, R.; Sopeña, B.; Blanco, R.; Unzurrunzaga, A.; Ortego-Centeno, N.; Marí-Alfonso, B.ña.; de Miguel, E.; Hidalgo-Conde, A.; Martín, J.; González-Gay, M.A. 2012: Autoimmune disease-associated CD226 gene variants are not involved in giant cell arteritis susceptibility in the Spanish population Clinical and Experimental Rheumatology 30(1 Suppl 70: S29-S33
Sinaga, B.Y.M.; Amin, M.; Siregar, Y.; Sarumpaet, S.M. 2014: Correlation between Vitamin D receptor gene FOKi and BSMi polymorphisms and the susceptibility to pulmonary tuberculosis in an Indonesian Batak-ethnic population Acta Medica Indonesiana 46(4): 275-282
Yu-Hong; Wu-Wei-Dong; Liu-Yu-Feng; Pu-Xiong-Ming; Shen-Zhu; Wu-Li-Feng 2007: Relationship of HCR gene polymorphism with psoriasis vulgaris in Uigur population of Xinjiang Uigur Autonomous Region, China Zhonghua Pifuke Zazhi 40(5): 293-295
Roy, S. 1995: L'itinérance : forme exemplaire d'exclusion sociale ? - Homelessness : an exemplary form of social exclusion ? - La itinerancia : ¿ una forma ejemplar de exclusión social ? Revue Internationale d'Action Communautaire (Montreal) (74): 73-80
Tozzi, F.; Bergen, A.W.; Bulik, C.M. 2002: Candidate gene studies in eating disorders Psychopharmacology Bulletin 36(3): 60-90
Ferguson-Smith, M.A. 1975: Gene mapping by exclusion Birth Defects Original Article Series 11(3): 126-129
Acharya, S.; Al-Elq, A.; Al-Nafaie, A.; Muzaheed, M.; Al-Ali, A. 2015: Type 2 diabetes mellitus susceptibility gene TCF7L2 is strongly associated with hyperglycemia in the Saudi Arabia Population of the eastern province of Saudi Arabia European Review for Medical and Pharmacological Sciences 19(16): 3100-3106
Zhuang, Q.-y.; Wu, Z.-h.; Qiu, G.-x. 2007: Is polymorphism of CALM1 gene or growth hormone receptor gene associated with susceptibility to adolescent idiopathic scoliosis? Zhonghua Yi Xue Za Zhi 87(31): 2198-2202
Hansen, L. 2003: Candidate genes and late-onset type 2 diabetes mellitus. Susceptibility genes or common polymorphisms? Danish Medical Bulletin 50(4): 320-346
Sluchanko, I.S. 1972: Various methodological problems in evaluating the health of a population (with reference to the article by Prof. L.E. Poliakov and medical sciences candidate D.M. Malinskiĭ: method of complex statistical evaluation of the health of a population) Sovetskoe Zdravookhranenie 31(6): 50-52
Munroe, P.B.; Johnston, A.; Duke, V.M.; Daniel, H.I.; Bouloux, P.M.; Lawson, M.; Caulfield, M.J. 1994: Investigation of lipoprotein lipase (LPL) as a candidate gene for dyslipidaemic hypertension Journal of Human Hypertension 8(8): 613-614
Von Deimling, A.; Albrecht, S.; Wiestler, O.D. 1994: Progression-associated gene regions in astrocytomas: a candidate locus on chromosome 19q Verhandlungen der Deutschen Gesellschaft für Pathologie 78: 423-426
Liu, J.; Lu, F.-h.; Wen, P.-e.; Jin, S.-k.; Wu, F.; Zhao, Y.-x.; Liu, Z.-d.; Sun, S.-w. 2005: The impact of gender factor on the candidate gene study of essential hypertension Zhonghua Xin Xue Guan Bing Za Zhi 33(11): 1010-1013