Mechanisms of gravity-dependent changes in the bone tissue
Rodionova, N.V.; Oganov, V.S.; Polkovenko, O.V.
Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 9(1): P169-P170
2002
ISSN/ISBN: 1077-9248 PMID: 15002533 Document Number: 541953
The most typical changes for the bone under the space flight conditions and a long-term hypokinesia are the following: the decreasing in bone mass, the demineralization and a reducing of a mechanical strength. It can lead to osteopenia and osteoporosis development. Also it increases the risk of fractures of supporting bones. Osteopenies, caused by the microgravity, are partially connected with the increasing of a reduction of trabecular bones. [Cytological mechanisms of gravity-dependent reactions in a bone tissue remain in many respects not clear. The study purpose was the analysis of some ultrastructural changes in bone tissue cells of the monkeys (Macaca mulatta), staying during 2 weeks onboard the biosatellite "Bion-11".