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Characteristics of the parallel-plate flow chamber for mechanical stimulation of bone cells under microgravity

Bacabac, R.G.; Smit, T.H.; Heethaar, R.M.; van Loon, J.J.W.A.; Pourquie, M.J.M.B.; Nieuwstadt, F.T.M.; Klein-Nulend, J.

Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 9(1): P181-P182

2002

ISSN/ISBN: 1077-9248
PMID: 19180754
Document Number: 541708
We show the use of a dimensionless parameter alpha h, in properly downscaling a parallel-plate flow chamber system for flow stimulation of bone cells under microgravity. The proper experimental regime for exposing cells to predictable levels of dynamic fluid shear stress requires: 1) alpha h < 2, based on the consequent quasi-parabolic form of the velocity profile in this regime, and 2) fo m<fc, where the critical frequency fc is the upper threshold for this flow regime, m is the highest harmonic mode of the flow, and fo is the fundamental frequency of fluid flow.

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Markham, S.M.; Rock, J.A. 1989: Deploying and testing an expandable surgical chamber in microgravity Aviation Space and Environmental Medicine 60(1): 76-79
Guo, Z.; Gong, X.; Li, Y.; Qiu, X.; Zhang, M.; Shangguan, T.; Ao, Q.; Liu, Q. 2015: Anatomical Plate Combined with Cortical Bone Plate Allografts for Treatment of Comminuted Fractures of Femoral Condyles Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 29(1): 6-9
Izzi, T.; Fontebuoni, A.; Talevi, N.; Lucarelli, G. 1981: Diffusion chamber cultures of bone marrow cells in refractory anemia with excess oil blasts (RAEB) Haematologica 66(5): 570-578
Ganser, A.; Hoelzer, D. 1984: Growth kinetics of CFU-GEMM, BFU-E, and CFU-C in diffusion-chamber cultures of normal human bone marrow cells Experimental Hematology 12(9): 712-716
Markolf, K.L.; Kabo, J.M.; Stoller, D.W.; Zager, S.A.; Amstutz, H.C. 1984: Flow characteristics of acrylic bone cements Clinical Orthopaedics and Related Research 183: 246-254
Ohl, S.; Chikkappa, G.; Cronkite, E.P. 1975: Diffusion-chamber cultures of bone marrow and peripheral blood from osteomyelosis patients: maturation and number of precursor cells Verhandlungen der Deutschen Gesellschaft für Innere Medizin 81: 1085-1087
Arbeille, P.; Achaïbou, F.; Fomina, G.; Pottier, J.M.; Porcher, M. 1996: Regional blood flow in microgravity: adaptation and deconditioning Medicine and Science in Sports and Exercise 28(10 Suppl): S70-S79
Keĭlis-Borok, I.V.; Latsinik, N.V.; Deriglazova, I.F. 1972: Characteristics of bone marrow cells--precursors of fibroblast-like cells according to their incorporation of thymidine-h 3 Biulleten' Eksperimental'noi Biologii i Meditsiny 73(10): 91-93
Morris, D.W.; Kim, C.Y.; Mcpherson, A. 1989: Automation of protein crystallization trials: use of a robot to deliver reagents to a novel multi-chamber vapor diffusion plate Biotechniques 7(5): 522-527
Sredni, B.; Friedman, M.M.; Bland, C.E.; Metcalfe, D.D. 1983: Ultrastructural, biochemical, and functional characteristics of histamine-containing cells cloned from mouse bone marrow: tentative identification as mucosal mast cells Journal of Immunology 131(2): 915-922
Gasparian, G.G.; Grigorian, R.M. 1989: The characteristics of the stimulation of the proliferation of cultured chick embryo cells during reseeding Tsitologiia i Genetika 23(5): 30-34
Subrahmanyam, V.; Sadler, A.; Suba, E.; Ross, D. 1989: Stimulation of in vitro bioactivation of hydroquinone by phenol in bone marrow cells Drug Metabolism and Disposition: the Biological Fate of Chemicals 17(3): 348-350
Salikhov, B.N.; Khamraev, A. 1991: Characteristics of interstitial cells of the adrenal medulla after stimulation of prostaglandin production by lasix Biulleten' Eksperimental'noi Biologii i Meditsiny 111(1): 46-48
Albrektsson, T.; Eriksson, A.R.; Jacobsson, M.; Kälebo, P.; Strid, K.G.; Tjellström, A. 1989: Bone repair in implant models: a review with emphasis on the harvest chamber for bone regeneration studies International Journal of Oral and Maxillofacial Implants 4(1): 45-54
Nilsson, P.; Albrektsson, T.; Granstrom, G.; Rockert, H.O. 1988: The effect of hyperbaric oxygen treatment on bone regeneration: an experimental study using the bone harvest chamber in the rabbit International Journal of Oral and Maxillofacial Implants 3(1): 43-48
Sukovatykh, B.S.; Orlova, A.I. 2017: Stimulation of angiogenesis by bone marrow cells in experimental ischaemia of lower limb Angiologiia i Sosudistaia Khirurgiia 23(1): 43-50
Shahid, R.; Mushtaq, A.; Maqsood, M. 2007: Plate fixation of clavicle fractures: a comparative study between Reconstruction Plate and Dynamic Compression Plate Acta Orthopaedica Belgica 73(2): 170-174
Antuf'ev, I.A. 1979: Simple flow chamber for embryos Arkhiv Anatomii Gistologii i Embriologii 77(7): 89-91