Renoprotective effect of monopril in patients with diabetes mellitus in the preclinical stage of diabetic nephropathy
Lapchyns'ka, I.I.; Zhurylo, T.I.; Seliuk, M.M.; Hromova, A.I.
Likars'ka Sprava 2002(5-6): 91-93
2002
ISSN/ISBN: 1019-5297 PMID: 12442535 Document Number: 541505
As many as 15 patients with insulin-dependent diabetes mellitus received monopril in a dose of 5 mg daily. Studied in the patients was the drug effect on the functional renal reserve and glomerular filtration rate. Determination of the functional renal reserve has been shown to be a criterion for an early diagnosis of the preclinical stage of diabetic nephropathy. Administration of monopril in exhausted functional renal reserve permits preventing development of proteinuria or allows a lapse of time for it to develop.