Acid-base state in rats with different resistance to hypoxia in experimental tracheal stenosis
Dzhabbarova, D.R.; Karimov, K.I.
Likars'ka Sprava 8: 110-113
2002
ISSN/ISBN: 1019-5297 PMID: 12669560 Document Number: 541193
Rats with different resistance to hypoxic hypoxia differ in parameters of their acid-base state: in high resistance, lower values for blood pH are recordable together with slightly higher pCO2 and content of non-volatile acids. Development of experimental stenosis of trachea in low- and high-resistant animals has been shown to significantly disturb the acid-base state (particularly in low-resistant rats). This process is compensatory-adaptive; it is characterized by development of respiratory acidosis at day 1 to 3, with the indices tending to return to the normal range at day 7, mixed acidosis developing later on.