Leptospirosis-clinico-biological and therapeutical aspects-study of 256 cases
Luca, M.C.ăt.ăl.; Dorobăţ, C.; Corcaci, C.; Scurtu, R.; Luca, V.; Mihalache, D.
Revista Medico-Chirurgicala a Societatii de Medici Si Naturalisti Din Iasi 107(2): 352-355
2002
ISSN/ISBN: 0048-7848 PMID: 12638290 Document Number: 540660
Leptospirosis is a zooantroponosis manifested as an infectious disease with a severe evolution, with liver and renal failure and hemorrhagic manifestation. The aim of this study was to present the clinico-biological investigation and the therapeutical aspects of 256 cases of leptospirosis admitted in the Infectious Diseases Hospital Iasi during 4 years (1998-2001). The diagnosis was based on the study of clinico-biological and therapeutical parameters (risk factors, fever, mialgia, headache, algic, eruptive, meningeal, hepatorenal, hemorrhagic syndromes with the serological evidence of the serotypes of leptospirosis); most of the cases were registered in 1998 (23% cases), in adults (31.2%) and male (75.22%). All the patients were serologic confirmed with leptospirosis (RAL and RFC), and L. icterohaemorhagiae was isolated most frequently. The standard anti-leptospirosis treatment was administered with favorable evolution; 6 deaths were registered from the severe forms of the disease. The leptospirosis is an emergent disease with the possibility of severe evolution in some forms, with liver and renal failure.