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Specific prophylaxis of influenza in organized groups of children with the vaccine Vaxigrip

Zaplatnikov, A.L.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 6: 36-40

2001

ISSN/ISBN: 0372-9311
PMID: 11881493
Document Number: 540551
The results of the open comparative study on epidemiological effectiveness and tolerance of the vaccine Vaxigrip, carried out in 109 children aged 2-15 years with different initial state of health, are presented. The index of epidemiological effectiveness of Vaxigrip was 4.09 (p < 0.05), the rate of epidemiological effectiveness--75.6% (p < 0.05). Vaxigrip was found to be well tolerated by both healthy children and those with different functional disturbances and chronic diseases. The study revealed that the use of Vaxigrip was not accompanied by any systemic postvaccinal reactions. High prophylactic effectiveness and good tolerance of Vaxigrip make it possible to recommend it for mass immunoprophylaxis of influenza in children.

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