Ataxic form of Guillain-Barré syndrome associated with anti-GD1b IgG antibody

Ichikawa, H.; Susuki, K.; Yuki, N.; Kawamura, M.

Rinsho Shinkeigaku 41(8): 523-525

2001


ISSN/ISBN: 0009-918X
PMID: 11889840
Document Number: 536841
A 28-year-old man was admitted after developing acute onset unstable gait following acute enteritis. Neurological examination revealed mild weakness in four limbs, areflexia and ataxia. Serum obtained from the patient during the acute stage contained a high titer of anti-GD1b IgG antibody. Because the patient showed obvious cerebellar ataxia unrelated to muscle weakness, without ophthalmoplegia or proprioceptive sensory disturbance, we concluded that he had ataxic form of Guillain-Barré syndrome (GBS) (Richter, 1962). Although ataxic GBS is not an established conception, one should pay attention to the possible existence of such a rare GBS variant. It is necessary to accumulate additional case reports to clarify the association between ataxic GBS and anti-ganglioside antibodies.

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