Cowden syndrome: clinical case presentation with oral lesions
Almenar Besó, R.; Vicente Bagán Sebastián, J.; Milián Masanet, M.A.; Jiménez Soriano, Y.
Anales de Medicina Interna 18(8): 426-428
2001
ISSN/ISBN: 0212-7199 PMID: 11589081 Document Number: 536664
Cowden syndrome is an autosomal-dominant inheritance disease, characterized by the presence of skin and oral mucosa multiple hamartomas and nodules, together with thyroid and breast anomalies and polyposis of the gastrointestinal tract, which tend to undergo malignant transformation, especially in breast and thyroids. Therefore, the oral lesions early diagnosis facilitates the identification of asintomatic lesions, in other parts of the body. This is the case in the report we are to present, in which the patient, probably with the Cowden Syndrome, because of the presence of multiple hamartomas in the oral mucose diagnosed a breast carcinoma, and other alterations such as thyroid calcifications and polyposis of the gastrointestinal tract.