LCAT (lecithin:cholesterol acyltransferase)
Kinoshita, M.; Teramoto, T.
Rinsho Byori. Japanese Journal of Clinical Pathology Suppl 116: 125-130
2001
ISSN/ISBN: 0047-1860 PMID: 11797372 Document Number: 534181
Lecithin:cholesterol acyltransferase (LCAT) is an enzyme which converts free cholesterol of lipoprotein into esterified cholesterol. LCAT plays an important role in lipid metabolism especially in the reverse cholesterol transport system. As LCAT protein is synthesized by the liver, patients with liver disease showed a decreased ratio of cholesteryl ester to total cholesterol. Familial LCAT Deficiency and Fish Eye Disease are disorders that lack LCAT activity congenitally.