Effect of hypergravity on the oxidative-antioxidative status of rats

Karbashevs'ka, N.I.; Oliĭnyk, S.A.; Bilokin', I.M.; Baraboĭ, V.A.; Hrynevych, I.P.

Fiziolohichnyi Zhurnal 47(5): 77-81

2001


ISSN/ISBN: 2522-9028
PMID: 11758473
Document Number: 532328
The adaptogenic and antioxidant properties of new Ukrainian plant drug "Poliphytolum" was investigated on the model of stress, which was caused of hypergravitation 2 and 5 N.m2/kg2 action. It was established that hypergravitation makes typical stressory disturbances in oxidative homeostasis. The normalization action of "Polyphytolum" on lipid peroxidation is more strong in liver, spleen and blood, and less more--in brain. It may be caused of low level the drug in the brain tissue.

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