Morphological studies of endocrine cells of the pancreas in rats after exposure to micro- and hypergravity
Alekseev, E.I.; Krasnov, I.B.
Aviakosmicheskaia i Ekologicheskaia Meditsina 29(1): 37-42
1995
ISSN/ISBN: 0233-528X PMID: 7663474 Document Number: 445947
Effects of changed gravity on the function of insulin-producing beta-cells and glucagon-producing alpha-cells in pancreas of rats after the 14-day missions of Cosmos-1887, -2044, and those pre- and postnatal development of which till day 60 proceeded at 2 G in a permanently rotating ground centrifuge were studied with the use of morphological techniques. The comparison of beta- and alpha-cells from pancreas of rats flown in space and subjected to relatively reduced gravity after transition from 2 G to 1 G in the laboratory experiment allow to deduce that the postflight reduced production of insulin by beta-cells and glucagon by alpha-cells has been caused by microgravity, whereas the hindered secretion of hormones is associated with the gravity stress within the first hours after recovery.