Lyposomal form of doxorubicin hydrochloride lypodox in the treatment of lymphogranulomatosis and non-Hodgkin's lymphomas
Ponamareva, O.V.; Kindzel'skiĭ, L.P.; Kulik, G.I.
Likars'ka Sprava 1: 112-117
2001
ISSN/ISBN: 1019-5297 PMID: 15311711 Document Number: 531484
The article focuses on the possibility of our employing the drug preparation lypodox, a lyposomal form of doxorubicini hydrochloridum, of the Byolek firm, in treating of Hodgkin's disease and non-Hodgkin's lymphomas. A comparative analysis was performed of efficacy and ill effects of lyposomal and free forms of doxorubicini hydrochloridum. It has been shown that by clinical effectiveness the drug preparation lypodox, doxorubicini hydrochloridum in a lyposomal form, is superior to doxorubicini hydrochloridum in a free form in resistant and aggressive forms of Hodgkin's disease and non-Hodgkin's lymphomas. Side reactions developing in the wake of lypodox administration do not threaten the life and health of patients; these do not preclude us from employing the drug in a clinical setting.