Top Abstract Purchase Related
Home
>
Node
>
Subnode

VP-16-213 in combination with cyclophosphamide, doxorubicin, vincristine, and prednisone in the treatment of non-Hodgkin's lymphomas

Hansen, M.M.; Bloomfield, C.D.; Jørgensen, J.; Ersbøll, J.; Pedersen-Bjergaard, J.; Blom, J.; Nissen, N.I.

Cancer Treatment Reports 64(10-11): 1135-1137

1980

ISSN/ISBN: 0361-5960
PMID: 7459900
Document Number: 166068
VP-16-213 has been used in 5-day courses together with cyclophosphamide, doxorubicin (Adriamycin), vincristine, and prednisone for treatment of 74 consecutive patients with non-Hodgkin's lymphomas. Ninety-one percent of patients with favourable histology and 69% with unfavorable histology achieved complete or partial remissions (overall response rate of 76%). The frequency of complete remission was disappointingly low (22%), possibly due to reduction of doses of the other myelosuppressive agents in the present combination. Further trials with VP-16-213 in other combination chemotherapy are required.

Document emailed within 1 workday
Secure & encrypted payments

Hainsworth, J.D.; Wolff, S.N.; Stein, R.S.; Greer, J.P.; Cousar, J.B.; Greco, F.A. 1986: Effects of Mega-COMLA (cyclophosphamide, cytarabine, vincristine, and methotrexate followed by leucovorin and prednisone) plus CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone) in the treatment of lymphoid neoplasms with very poor prognosis Cancer Treatment Reports 70(8): 953-958
Miller, T.P.; Jones, S.E.; Rainey, J.M. 1983: Cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) in patients with advanced Hodgkin's disease: a Southwest Oncology Group Phase Ii Study Cancer Treatment Reports 67(7-8): 739-740
Bezwoda, W.R.; Rastogi, R.B. 1994: A randomized comparative study of cyclophosphamide, vincristine, doxorubicin, and prednisolone and cyclophosphamide, vincristine, mitoxantrone, and prednisolone regimens in the treatment of intermediate- and high-grade lymphoma with 8 years' follow-up Seminars in Hematology 31(2 Suppl 3: 3
Durant, J.R.; Gams, R.A.; Bartolucci, A.A.; Dorfman, R.F. 1977: BCNU with and without cyclophosphamide, vincristine, and prednisone (COP) and cycle-active therapy in non-Hodgkin's lymphoma Cancer Treatment Reports 61(6): 1085-1096
Tirelli, U.; Carbone, A.; Veronesi, A.; Galligioni, E.; Trovò, M.G.; Tumolo, S.; Grigoletto, E. 1982: Combination chemotherapy with cyclophosphamide, vincristine, and prednisone (CVP) in TNM-classified stage IV mycosis fungoides Cancer Treatment Reports 66(1): 167-169
Lauria, F.; Baccarani, M.; Fiacchini, M.; Frezza, R.; Gobbi, M.; Tura, S. 1978: 5-year survey of methotrexate, cyclophosphamide (Endoxan), and vincristine (MEV) therapy for advanced non-Hodgkin's lymphomas Cancer Treatment Reports 62(8): 1193-1197
Whitecar, J.P.; Bodey, G.P.; Freireich, E.J.; McCredie, K.B.; Hart, J.S. 1972: Cyclophosphamide (NSC-26271), vincristine (NSC-67574), cytosine arabinoside (NSC-63878), and prednisone (NSC-10023) (COAP) combination chemotherapy for acute leukemia in adults Cancer ChemoTherapy Reports 56(4): 543-550
Brun, B.; Kuentz, M.; Man, N.G.; Feuilhade, F.; Bierling, P.; Vernant, J.P.; Farcet, J.P.; Cordonnier, C.; Reyes, F.; Dreyfus, B.; Rochant, H. 1983: Multiple myeloma with high tumoral mass. Treatment combining melphalan, cyclophosphamide, vincristine, CCNU and prednisone. 35 cases Presse Medicale 12(19): 1205-1210
Bilgi, O.; Karagoz, B.; Alacacioglu, A.; Ozgun, A.; Tuncel, T.; Gokhan-Kandemir, E. 2010: Irinotecan and cisplatin vs. cyclophosphamide, doxorubicin, and vincristine as second-line treatment after platinum and etoposide in small-cell lung cancer Journal of BUON: Official Journal of the Balkan Union of Oncology 15(2): 395
Robert, J.; Vrignaud, P.; Iliadis, A.; Eghbali, H.; Hoerni, B. 1983: Pharmacokinetic study of doxorubicin in the treatment of malignant non-Hodgkin's lymphomas Nouvelle Revue Francaise d'Hematologie 25(2): 91-95
Huang, H.; Lian, L.; Huang, R. 1995: Response of ovarian endodermal sinus tumor to combination chemotherapy with cis-platinum, vincristine and bleomycin or vincristine, actinomycin and cyclophosphamide Zhonghua Fu Chan Ke Za Zhi 30(5): 265-269
Ponamareva, O.V.; Kindzel'skiĭ, L.P.; Kulik, G.I. 2001: Lyposomal form of doxorubicin hydrochloride lypodox in the treatment of lymphogranulomatosis and non-Hodgkin's lymphomas Likars'ka Sprava 1: 112-117
Middleton, J.; Franks, D.; Buchanan, R.B.; Hall, V.; Smallwood, J.; Williams, C.J. 1985: Failure of scalp hypothermia to prevent hair loss when cyclophosphamide is added to doxorubicin and vincristine Cancer Treatment Reports 69(4): 373-375
Komarnicki, M.; Balcerzak, A.; Górski, P.; Pawlak, L.; Hansz, J. 1994: Treatment outcome of advanced Hodgkin's disease based on using an alternating program ChLVPP (chlorambucil, vinblastine, procarbazine, prednisone) and ABV (doxorubicin, bleomycin, vinblastine) Acta Haematologica Polonica 25(4): 363-368
Merli, F.; Federico, M.; Avanzini, P.; Ilariucci, F.; Stelitano, C.; Iannitto, E.; Colombi, M.; Vallisa, D.; Santagati, G.; Picinini, L. 1998: Weekly administration of vincristine, cyclophosphamide, mitoxantrone and bleomycin (VEMB) in the treatment of elderly aggressive non Hodgkin's lymphoma. Gruppo Italiano per lo Studio dei Linfomi Haematologica 83(3): 217-221
Williams, S.D.; Einhorn, L.H. 1977: Combination chemotherapy with doxorubicin and lomustine. Treatment of refractory Hodgkin's disease JAMA 238(15): 1659-1661
Nowak, C.; Arnold, W.; Henneberger, G.; Tanneberger, S. 1980: Therapeutic effectiveness of carminomycin (CRM) in combination with dibromodulcitol (DBD) compared with the combination vincristine, cyclophosphamide, methotrexate, 5-fluorouracil (VCMF) on some tumor systems Archiv für Geschwulstforschung 50(8): 747-757
Diehl, L.F.; Perry, D.J.; Terebelo, H.; Baldwin, P.E.; Hurwitz, M.; Kimball, D.B.; Dorn, R.V. 1983: Radiation as salvage therapy for patients with Hodgkin's disease relapsing after MOPP (mechlorethamine, vincristine, prednisone, and procarbazine) chemotherapy Cancer Treatment Reports 67(9): 827-829
Leone, G.; Pagano, L.; Marra, R.; Landolfi, R.; Cudillo, L.; Storti, S.; Mango, G.; Alfano, G.; D'Onofrio, G. 1987: Combination of 6-mercaptopurine, vincristine, methotrexate, and prednisone in resistant or relapsed acute nonlymphoid leukemia Cancer Treatment Reports 71(7-8): 751-753
Burns, C.P. 1975: Daunorubicin (NSC-82151), vincristine (NSC-67574), cytosine arabinoside (NSC-63878), and prednisone (NSC-10023) combination therapy for advanced adult acute leukemia Cancer ChemoTherapy Reports 59(4): 757-760