Drug-induced heart failure
Negrusz-Kawecka, M.
Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 11(63): 271-275
2001
ISSN/ISBN: 1426-9686 PMID: 11761828 Document Number: 530898
Heart failure is a clinical syndrome caused mainly by cardiovascular diseases such as coronary heart disease, hypertension and valvular disease, but several categories of drugs may potentially induce heart failure in patients without previous heart disease or precipitate revealing of heart failure symptoms in patients with preexisting left ventricle impairment. Pathophysiologically drugs that increase preload, afterload or have negative inotropic properties may be able to cause this adverse reaction. In the article the potential role in the occurrence of heart failure of cytostatics, immunomodulating drugs, nonsteroidal anti-inflammatory drugs, calcium channel blockers, beta-adrenoceptor antagonists, antiarrhythmics, anesthetics and antidepressants is reviewed.