Type a botulinum toxin in the treatment of chronic facial pain associated with temporo-mandibular dysfunction
Von Lindern, J.J.
Acta Neurologica Belgica 101(1): 39-41
2001
ISSN/ISBN: 0300-9009 PMID: 11379274 Document Number: 528754
In an open-label study 41 patients suffering from the muscular form of temporo-mandibular dysfunction were treated with botulinum toxin type A injections into masticatory muscles (average of 200 U on each side) and followed for an average of 6.7 months. Eighty percent of patients improved by a mean reduction of 45% on a visual analogue pain scale. During the observation period, 17% of patients had to receive a second injection because of recurrent pain. Reversible speech and swallowing difficulties occurred in only 1 patient. These encouraging results need to be confirmed by a randomized controlled trial.