Electrical properties of intact rabbit aortic endothelium

Iarots'kyĭ, V.V.; Sagach, V.F.; Marchenko, S.M.

Fiziolohichnyi Zhurnal 47(1): 9-16

2001


ISSN/ISBN: 2522-9028
PMID: 11296564
Document Number: 528546
The ionic nature of membrane potential and electrical reactions to vasodilators and vasoconstrictors of intact endothelium of rabbit aorta have been investigated. It has been shown that K+ and Na+, but not Cl- permeability form membrane resting potential. The endothelium was hyperpolarized by ACh. ATP produced the triphasic reaction of short small depolarization, hyperpolarization followed by depolarization. Both noradrenalin and serotonin evoked depolarization.

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