Primitive seminoma of the mediastinum: a case report
Tahri, A.; Sahraoui, S.; Bouras, N.; Benchekroun, N.; Acharki, A.; Benider, A.; Kahlain, A.
Annales d'Urologie 35(1): 64-66
2001
ISSN/ISBN: 0003-4401 PMID: 11233327 Document Number: 527857
In this study, the case has been reported of a 36-year old male who was treated at the Ibn Rochd Oncology Center in Casablanca for a primary mediastinal seminoma revealed by a symptomatology including cough, dyspnea, laterocervical swelling, rachidial pain and gait disorder. The preliminary investigation showed significant mediastinal enlargement with a right pleuritis and vertebral metastases; tumor markers were normal. The diagnosis of seminoma was confirmed by pathological and immunohistochemical analysis of the cervical adenopathy. Disease management consisted of BEP/cisplatin type chemotherapy and lumbar, mediastinal, and supraclavicular radiotherapy. The response after four courses of combined chemo-/radiotherapy was estimated at 25%, but the patient died from respiratory failure five months after the initiation of treatment.