About side effects of platinum drugs
Waszkiewicz, K.
Postepy Higieny i Medycyny Doswiadczalnej 55(3): 387-406
2001
ISSN/ISBN: 0032-5449 PMID: 11505639 Document Number: 526427
The work presents current view about toxic effects of platinum anticancer drugs. In the first part, the toxic effects of cisplatin as nephrotoxicity, ototoxicity, myelosuppression, anaphylactic-like reactions, neurotoxicity and gastrotoxicity are presented. The second part describes mechanisms of nephrotoxicity of cisplatin. In the third part, the toxicity of carboplatin and iproplatin are reviewed.