Ischemic preconditioning decrease the release of cardiac troponin T during heart valve replacement
Jiang, H.H.; Chen, S.X.; Tang, Y.
Hunan Yi Ke da Xue Xue Bao 25(4): 399-400
2000
ISSN/ISBN: 1000-5625 PMID: 12206016 Document Number: 525596
Using cardiac troponin T(cTnT), a highly sensitive and specific marker of myocardial injury, we evaluated the effects of ischemic precondition on ischemic reperfusion myocardial injury. Thirty two patients were randomly divided into control group(n = 16) and ischemic preconditioning group(n = 16). The marker cTnT was measured in each group before operation, and 4 h, 24 h and 72 h after operation. The results showed that the peak value of cTnT was lower, and more quickly recovered in the preconditioning group than that in the control. It is suggested that ischemic preconditioning exert an evidently protective effect on ischemic reperfusion myocardial injury.