Spinal cord compression secondary to extramedullary hematopoiesis in a patient with thalassemia
Bruneteau, G.; Fénelon, G.; Khalil, A.; Kanfer, A.; Girot, R.
Revue Neurologique (Paris) 156(5): 510-513
2000
ISSN/ISBN: 0035-3787 PMID: 10844371 Document Number: 523499
A 19-year-old man with homozygous beta thalassemia presented with signs of thoracic spinal cord compression secondary to extramedullary hematopoiesis. The patient was treated with hypertransfusion and hydroxyurea. After two months, clinical signs had resolved and magnetic resonance imaging showed significant regression of the extradural mass. Pathophysiology and therapeutic options in this condition are briefly discussed.
Document emailed within 1 workday
Related Documents
Fareed, S.; Soliman, A.T.; De Sanctis, V.; Kohla, S.; Soliman, D.; Khirfan, D.; Tambuerello, A.; Talaat, M.; Nashwan, A.; Caparrotti, P.; Yassin, M.A. 2017: Spinal cord compression secondary to extramedullary hematopoiesis: A rareness in a young adult with thalassemia major Acta Bio-Medica: Atenei Parmensis 88(2): 237-242Rey, J.; Gagliano, R.; Christides, C.; Pillard, E.; Magnan, F.; Tourniaire, P.; Arwidson, I.; Raymond-Gelle, M.C.; Boulat, O.; Arlaud, J. 2001: Spinal cord compression caused by extramedullary hematopoiesis foci in the course of thalassemia Presse Medicale 30(27): 1351-1353
Price, F.; Bell, H. 1985: Spinal cord compression due to extramedullary hematopoiesis. Successful treatment in a patient with long-standing myelofibrosis JAMA 253(19): 2876-2877
Julien, J.; Broustet, A.; Trojani, M.; Riemens, V.; Lagueny, A.; Reiffers, J.; Demassieux, V. 1981: Spinal cord compression by extramedullary hematopoiesis in chronic eosinophilic leukemia La Semaine des Hopitaux: Organe Fonde Par l'Association d'Enseignement Medical des Hopitaux de Paris 57(11-12): 598-600
Russo, D.; Pileri, S.; Barbieri, E.; Bandini, G.; Zaccaria, A.; Benfenati, D.; Bernardi, B.; Trevisan, C.; Busacca, M.; Babini, L. 1989: Spinal cord compression by extramedullary hematopoietic tissue in a thalassemic patient: prompt effect of radiotherapy Haematologica 74(5): 495-498
Newton, K.L.; McNeeley, S.G.; Novick, M. 1983: Extramedullary hematopoiesis presenting as a pelvic mass in a patient with beta-thalassemia intermedia JAMA 250(16): 2178-2179
Tantraworasin, A.; Saeteng, S. 2013: Massive hemothorax due to intrathoracic extramedullary hematopoiesis in a patient with beta thalassemia hemoglobin e disease Journal of the Medical Association of Thailand 96(7): 866-869
Ben-Bassat, I.; Hertz, M.; Selzer, G.; Ramot, B. 1977: Extramedullary hematopoiesis with multiple tumor-simulating mediastinal masses in a patient with beta-thalassemia intermedia Israel Journal of Medical Sciences 13(12): 1206-1210
Yu, Y.C.; Kao, E.L.; Chou, S.H.; Lin, T.J.; Chien, C.H. 1991: Intrathoracic extramedullary hematopoiesis simulating posterior mediastinal mass--report of a case in patient with beta-thalassemia intermedia Gaoxiong Yi Xue Ke Xue Za Zhi 7(1): 43-48
Ahmed, F.; Tobin, M.S.; Cohen, D.F.; Gomez-Leon, G. 1981: Beta thalassemia. Spinal cord compression New York State Journal of Medicine 81(10): 1505-1508
Issaragrisil, S.; Piankigagum, A.; Wasi, P. 1981: Spinal cord compression in thalassemia. Report of 12 cases and recommendations for treatment Archives of Internal Medicine 141(8): 1033-1036
Pagès, A.; Pagès, M.; Ramos, J. 1988: Compression of the cauda equina due to extramedullary hematopoiesis Annales de Pathologie 8(1): 61-63
Sudo, N. 1980: Clinical application of the evoked spinal cord potentials. Part 1. Neurophysiological assessment of the evoked spinal cord potentials in experimental cord trauma - with reference to cord compression and ischemia Nihon Seikeigeka Gakkai Zasshi 54(12): 1631-1647
Teawtrakul, N.; Chansung, K.; Sirijerachai, C.; Pongudom, S.; Jetsrisuparb, A. 2017: A Clinical Risk Score for Predicting Paraspinal Extramedullary Hematopoiesis in Patients with Thalassemia: the KKU-EMH Score Journal of the Medical Association of Thailand 100(4): 389-395
Casino, C.M.; Blando, A.V. 1994: Calcification of ligamentum flavum causing spinal cord compression in a stroke patient Archives of Physical Medicine and Rehabilitation 75(2): 226-228
Rao, S.C.; Fehlings, M.G. 1999: The optimal radiologic method for assessing spinal canal compromise and cord compression in patients with cervical spinal cord injury. Part I: An evidence-based analysis of the published literature Spine 24(6): 598-604
Wipff, J.; Allanore, Y.; Cormier, C.; Redondo, Aée.; Kahan, Aé. 2005: Ossification of the common posterior longitudinal ligament of the spine and spinal cord compression in a patient from Senegal Presse Medicale 34(9): 655-656
Jiménez, C.; Bustos, M.; Besses, C. 2001: The irreplaceable image: a patient with subacute degeneration of the spinal cord secondary to pernicious anemia Haematologica 86(4): 444
Milionis, H.J.; Dimitra, R.; Elisaf, M.S. 1998: Extramedullary hemopoiesis in a patient with beta-thalassemia trait International Journal of Hematology 67(1): 87-89
Reith, C.; Reith, H.B.; Baumgärtner, D.; Kozuschek, W.; Lausberg, G. 1991: Diagnosis and interdisciplinary therapy of spinal cord compression caused by spinal metastases Zentralblatt für Chirurgie 116(15): 913-916