A case of isolated ACTH deficiency presenting with hypercalcaemia
Wong, R.K.; Gregory, R.; Lo, T.C.
International Journal of Clinical Practice 54(9): 623-624
2000
ISSN/ISBN: 1368-5031 PMID: 11220994 Document Number: 523305
A 76-year-old man presented with a subacute history of weight loss, malaise and anorexia. Laboratory investigations revealed serially increasing hypercalcaemia, correlating with deterioration in his clinical status. He was subsequently shown to have hypocortisolaemia, which improved with the administration of intravenous steroids. Subsequent biochemical testing revealed the endocrinological defect to be one of isolated ACTH deficiency, which, unlike Addison's disease, does not classically include hypercalcaemia in its presentation.