Bone ultrastructural changes in Bion 11 rhesus monkeys
Rodionova, N.V.; Shevel, I.M.; Oganov, V.S.; Novikov, V.E.; Kabitskaya, O.E.
Journal of Gravitational Physiology a Journal of the International Society for Gravitational Physiology 7(1): S157-S161
2000
ISSN/ISBN: 1077-9248 PMID: 11543449 Document Number: 519654
Iliac crest biopsies of Bion 11 monkeys were examined by electron microscopy. The flight samples contained a large number of inactive osteoblasts. Together with ultrastructural changes of the rough endoplasmic reticulum and the Golgi complex, the predominance of inactive osteoblasts pointed to a lower rate of specific syntheses. Some osteoblasts were transformed to fibroblast-like cells. It was found that osteogenesis declined, osteoid mineralization changed, and fibrotic zones developed.