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Singular anti-RNA virus-directed proteins

Rayanade, R.J.; Banerjee, K.; Shirodkar, M.V.

Journal of Postgraduate Medicine 46(3): 164-171

2000

ISSN/ISBN: 0022-3859
PMID: 11298462
Document Number: 518865
To additionally purify and characterise the anti-RNA virus-directed protein termed p14. Antiviral assays of p14 against RNA and DNA viruses were carried out and its antigenic similarities with chicken interferon (CIFN) were studied. HPLC-Reverse Phase of p14 was performed to further purify p14. p14 showed antiviral activity against RNA viruses only and not against DNA viruses. It was antigenically distinct from CIFN. Purification of p14 yielded three proteins with antiviral activity, which had different physico-chemical properties than those described for interferons. The data presented on the antiviral, immunological and physico-chemical properties, establish the unique nature of p14 vis-á-vis those of interferons.

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Youngren, S.D.; Vukasin, A.P.; de Noronha, F. 1984: Characterization of monoclonal antibodies directed against the envelope proteins of feline leukemia virus Cancer Research 44(8): 3512-3517
Barocci, S.; Fenoglio, D.; Leprini, A.; Nocera, A. 1990: Anti-HLA antibodies (Ab1) and anti-idiotypic antibodies (Ab2) directed against Anti-HLA Ab1 in various preparations of polyspecific immunoglobulins for intravenous use Bollettino della Societa Italiana di Biologia Sperimentale 66(12): 1193-1200
Edson, C.M.; Cohen, L.K.; Henle, W.; Strominger, J.L. 1983: An unusually high-titer human anti-Epstein Barr virus (EBV) serum and its use in the study of EBV-specific proteins synthesized in vitro and in vivo Journal of Immunology 130(2): 919-924
Brake, A.J. 1990: Alpha-factor leader-directed secretion of heterologous proteins from yeast Methods in Enzymology 185: 408-421
Popa, L.M. 1971: Synthesis of proteins in a cell-free medium directed by messenger nucleic acids Studii Si Cercetari de Inframicrobiologie 22(6): 593-598
Bringmann, P.; Rinke, J.; Appel, B.; Reuter, R.; Lührmann, R. 1983: Purification of sn RNPs U1, U2, U4, U5 and U6 with 2,2,7-trimethylguanosine-specific antibody and definition of their constituent proteins reacting with anti-Sm and anti-(U1) RNP antisera EMBO Journal 2(7): 1129-1135
Agius, M.A.; Geannopoulos, C.J.; Fairclough, R.H.; Richman, D.P. 1988: Monoclonal anti-idiotopic antibodies against myasthenia-inducing anti-acetylcholine receptor monoclonal antibodies. Preponderance of nonparatope-directed antibodies affecting antigen binding Journal of Immunology 140(1): 62-68
Zigangirova, N.A.; Fedina, E.D.; Zorina, V.V.; Bortsov, P.A.; Tokarskaia, E.A.; Kariagina, A.S.; Alekseevskiĭ, A.V.; Kraiushkin, M.M.; Zaiakin, E.S.; Iarovenko, V.N.; Gintsburg, A.L. 2009: Target-directed search of anti-virulence drugs Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 71-77
Fel'dman, O.L.; Blok, L.M.; Rosenberg, V.D.; Anokhina, H.O. 1975: Synthesis of RNA and proteins with exogenous template in the DNA-directed cell-free system from Escherichia coli B. after UV-irradiation Ukrains'kyi Biokhimichnyi Zhurnal 47(4): 417-421
Sahoo, S. 2016: Finding self-directed learning readiness and fostering self-directed learning through weekly assessment of self-directed learning topics during undergraduate clinical training in ophthalmology International Journal of Applied and Basic Medical Research 6(3): 166-169
Sahoo, S. 2016: Finding self-directed learning readiness and fostering self-directed learning through weekly assessment of self-directed learning topics during undergraduate clinical training in ophthalmology International Journal of Applied and Basic Medical Research 6(3): 166-169
Pontzer, C.H.; Yamamoto, J.K.; Bazer, F.W.; Ott, T.L.; Johnson, H.M. 1997: Potent anti-feline immunodeficiency virus and anti-human immunodeficiency virus effect of IFN-tau Journal of Immunology 158(9): 4351-4357
Staquet, M.J.; Kobayashi, Y.; Dezutter-Dambuyant, C.; Schmitt, D. 1995: Role of specific successive contacts between extracellular matrix proteins and epidermal Langerhans cells in the control of their directed migration European Journal of Cell Biology 66(4): 342-348
Chomik, M. 1978: Purification of influenza a virus and preliminary characterization of virus proteins by polyacrylamide gel electrophoresis (PAGE) Archivum Immunologiae et Therapiae Experimentalis 26(1-6): 537-540
Amvros'eva, T.V.; Itkin, Z.B.; Sklianskaia, E.I. 1983: Synthesis of virus-specific proteins in a mixed infection caused by various strains of influenza virus a and B Voprosy Virusologii 28(4): 90-96
Maes, M.; Mihaylova, I.; Leunis, J.-C. 2006: Chronic fatigue syndrome is accompanied by an IgM-related immune response directed against neopitopes formed by oxidative or nitrosative damage to lipids and proteins Neuro Endocrinology Letters 27(5): 615-621
Wang, R.; Wu, X.; Liu, L.; An, Y. 2014: Activity directed investigation on anti-inflammatory fractions and compounds from flowers of Trollius chinensis Pakistan Journal of Pharmaceutical Sciences 27(2): 285-288
Papko, G.F. 1971: New method of obtaining and clinical use of human anti-smallpox gamma globulin of directed action Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 48(2): 66-70
Loyter, A.; Beigel, M. 1982: Sendai virus envelope as a carrier for transferring membrane proteins: a quantitative estimation of virus-cell adsorption and fusion Progress in Clinical and Biological Research 102 Pt A: 337-345
McGinley, M.J.; Platt, K.B. 1989: Antibody response of pseudorabies virus subunit-vaccinated pigs to viral nucleocapsid proteins following low-dose virus challenge of immunity American Journal of Veterinary Research 50(8): 1290-1293