A clinical prospective study on maternal-fetal transfusion transmitted virus infection
Chen, H.; Wang, Y.; Pei, F.
Zhonghua Fu Chan Ke Za Zhi 35(5): 277-278
2000
ISSN/ISBN: 0529-567X PMID: 11775906 Document Number: 518366
To observe the transfusion transmitted virus (TTV) infection rate in gravidas and parturients, and explore the route of maternal-fetal transmission. TTV infection was detected by nest-polymerase chain reaction (n-PCR) in the serum of 60 healthy gravidas and parturientes. Once parturient infection was identified, the latices and the umbilical blood were examined for TTV infection as well. Meanwhile, a group of non-pregnant healthy women was tested as control. The infection rate of observation group was 28.33%, while in the control group it was 7.57%. The difference of the two groups was significant (P < 0.001). Of the TTV positive parturientes, TTV infection rate of their latices was 27.27%, but none of the umbilical blood samples showed TTV positive. The TTV infection rate of gravidas and parturientes is higher than that of non-pregnant healthy women. TTV can infect newborns through latices, however, there is no vertical maternal-fetal transmission.