Prognostic value of bcl-2, p53 and Ki-67 in invasive squamous carcinoma of the uterine cervix
Padovan, P.; Salmaso, R.; Marchetti, M.; Padovan, R.
European Journal of Gynaecological Oncology 21(3): 267-272
2000
ISSN/ISBN: 0392-2936 PMID: 10949392 Document Number: 517826
The aim of this study was to evaluate the immunohistochemical expression of the markers bcl-2, p53 and Ki67 and their relation to the classical clinical-pathological prognostic factors in invasive squamous cellular carcinoma of the cervix. Since bcl-2 and p53 are implicated in the regulation of programmed cell death, very probably they play a role in carcinogenesis and consequently become prognostic factors.
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