Multiple primaries of the upper aerodigestive tract, esophagus, and lung
García Cantos, M.; De Mier Morales, M.; Delgado Balufo, D.; Márquez García-Salazar, M.M.; Jaén Olazolo, J.; Porras Alonso, E.; Carrillo de Albornoz y Vargas, F.
Acta Otorrinolaringologica Espanola 51(2): 154-159
2000
ISSN/ISBN: 0001-6519 PMID: 10804118 Document Number: 517765
The existence of multiple primary tumors of the upper aerodigestive tract, esophagus, and lung (UADT-E-L) is related with a common etiopathogenic factor (alcohol-tobacco association). In a review of 43 patients, 6.75% with a UADT-E-L tumor developed another neoplasm, 3.25% at the same site. Nine percent (8.59%) of the tumors were synchronic and 10.85% were metachronic. The most frequent association was larynx-lung. Another neoplasm was detected by physical examination and/or radiology in 44.18% of cases, with a time lapse of less than 3 years in 50%. The most frequent treatment was surgery with/without complementary radiotherapy. The most common stage was T1-T2 (62.06%) and N0-N1 (68.96%). The survival rate was 31% at 2 years and 25% at 3 years.