Neoadjuvant chemotherapy with cis-platin and 5-fluorouracil in continuous infusion (96 h.), in stages IIi and IV of carcinomas of the upper aerodigestive tract

Muñoz, A.; Bernal, A.G.; Ramos, A.; Lavilla, M.J.; Martín, A.; Gómez, J.L.; Cruz, J.J.; Nieto, A.; del Cañizo, A.; Muñoz, A; Bernal, A.G; Ramos, A; Lavilla, M.J; Martín, A; Gómez, J.L; Cruz, J.J; Nieto, A; del Cañizo, A

Home

>

Node

>

Subnode

Neoadjuvant chemotherapy with cis-platin and 5-fluorouracil in continuous infusion (96 h.) , in stages IIi and IV of carcinomas of the upper aerodigestive tract

Muñoz, A.; Bernal, A.G.; Ramos, A.; Lavilla, M.J.; Martín, A.; Gómez, J.L.; Cruz, J.J.; Nieto, A.; del Cañizo, A.

Acta Otorrinolaringologica Espanola 42(1): 30-36

1991

ISSN/ISBN: 0001-6519

PMID: 2036258

Document Number: 376333

We have studied 37 patients with advanced head and neck cancer. A combination of Cis-Platinum and 5-Fluorouracil, both administered four days continuously as infusion, was assessed. There were 15 complete responses (40.5%), 15 partial responses (40.5%) and the number of objective responses was 30 (81.5%). Survival is 79.1% at 22 months and none of the patients in complete responses has relapsed during this period.