Cyclosporin in an oral microemulsion as the initial treatment of corticoid-refractory ulcerative colitis
Ortiz, V.; Nos, P.; Aguilera, V.; Berenguer, J.; Ponce, J.
Gastroenterologia y Hepatologia 23(3): 120-122
2000
ISSN/ISBN: 0210-5705 PMID: 10804688 Document Number: 517730
To assess the efficacy of oral microemulsion cyclosporin as the initial treatment of active ulcerative colitis refractory to steroid therapy. The evolution of five patients treated with a dose of 5 mg/kg/day was analyzed. Oral microemulsion cyclosporin controlled acute attacks of the disease and led to remission during the 3 months of treatment in four of the five patients. Average hospital stay was 5.5 days. Oral microemulsion cyclosporin is an effective treatment in ulcerative colitis. Its administration is simple, the use of venous catheters is avoided and it may reduce mean hospital stay.