Clinical management of avulsed permanent incisors using Emdogain: initial report of an investigation
Kenny, D.J.; Barrett, E.J.; Johnston, D.H.; Sigal, M.J.; Tenenbaum, H.C.
Journal 66(1): 21
2000
ISSN/ISBN: 0709-8936 PMID: 10859726 Document Number: 517631
The enamel matrix derivative Emdogain was recently approved for clinical use in a number of countries, including Canada. It has been shown to stimulate regeneration of periodontal ligament following periodontal surgery in adults. This paper reviews pertinent clinical and laboratory studies of Emdogain and describes the protocol and methods used for a longitudinal outcome study of replantation of avulsed permanent incisors in children and adolescents. Application of these methods is described in an illustrative case report of Emdogain use. This paper is meant to inform clinicians and guide those who are instituting similar investigations.