Development of a peristaltic inhibition model in mice
Cui, S.; Li, Y.; Li, Y.; Han, C.
Wei Sheng Yan Jiu 29(6): 385-386
2000
ISSN/ISBN: 1000-8020 PMID: 12520963 Document Number: 516954
Diphenoxylate was administered to mice at the dose of 5 mg/kg BW for the development of peristaltic inhibition model for formulating the examination procedure of health foods. An ink solution containing 5% charcoal was then administered 30 minutes later. The length of ink progradation of the small intestine of mice was calculated 25 minutes after the administration of ink. The results in this model was stable and reliable, and it was recommended to use this model to verify the function of health foods.
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