Electroencephalography in Creutzfeld-Jakob disease
Ortega-Albás, J.J.
Revista de Neurologia 31(2): 152-155
2000
ISSN/ISBN: 0210-0010 PMID: 10951673 Document Number: 516242
The electroencephalogram is very useful in the diagnosis of probable Creutzfeldt-Jakob disease. It is considered that a typical pattern is formed of periodic sharp wave complexes, widely distributed (synchronously and symmetrically) over both cerebral hemispheres. The frequency of presentation is approximately 1/second. However during the course of the disease other patterns are seen, such as frontal intermittent rhythmical delta activity, a cyclical alternating pattern and a low output electroencephalogram. Recognition of these patterns, their electroclinical correlation and serial polygraphic studies are very important to the reliability of the test.