Jakob-Creutzfeldt disease
Jirásek, A.
Ceskoslovenska Patologie 19(3): 133-137
1983
ISSN/ISBN: 1210-7875 PMID: 6354480 Document Number: 202844
Jakob - Creutzfeldt disease (JC) occurs commonly in this country and its diagnosis is made by clinicians, according to retrospective analysis of 11 cases. This material was not sufficient for endemic or familiar background to be taken into consideration. Cases, diagnosis of which was not made by clinician, needed a neuropathologist perfectly informed about clinical and morphological picture of JC, and a qualified and rather extensive examination of CNS. The 11 cases were varied but features of Garcin - Sträussler syndrome were lacking among them. Morphological differential diagnosis included separation of spongiosis in JC from vasogenic oedema, beginning vascular lesion, metabolic encephalopathy and chronic encephalitis.