Treatment of advanced Parkinson's disease
Momose, Y.; Murata, M.; Kanazawa, I.
Nihon Rinsho. Japanese Journal of Clinical Medicine 58(10): 2061-2065
2000
ISSN/ISBN: 0047-1852 PMID: 11068447 Document Number: 514856
After the advent of levodopa, treatment of Parkinson's disease has changed and the activity of daily life of patients has been remarkably improved; whereas, many patients experience various problems such as wearing-off, dyskinesia, dystonia, neuropsychiatric problems, and dysautonomia. Especially, wearing-off and dyskinesia emerge with the change of absorptional pattern of levodopa and could be solved by regulating the timing and the dose of it. Recently, some new drugs for Parkinson's disease have been available and we physician have a wide choice of them. It is important to make a careful choice of and manipulate of doses of drugs after understanding daily life of each patient enough.