Development of biodegradable polymer scaffolds for bone tissue engineering
Zheng, L.; Wang, Q.; Pei, G.X.
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 14(3): 175-180
2000
ISSN/ISBN: 1002-1892 PMID: 12080858 Document Number: 514592
To investigate the selection and manufacture of ideal extracellular matrix materials in bone tissue engineering. The recent literatures about biodegradable polymers served as culture scaffolds of osteoblasts were widely reviewed, the advantages and disadvantages of biodegradable synthetic polymers and natural polymers were analysed. The ideal extracellular matrix material in bone tissue engineering should be made up of inorganic materials, synthetic polymers and natural polymers, which possesses morphological structure of three-dimensional foam with self-mediated drug slow delivery system of bone growth factors. The design and manufacture of combined extracellular matrix materials in bone tissue engineering is a very important and urgent challenge.