Benzocaine-induced methemoglobinemia
Gupta, P.M.; Lala, D.S.; Arsura, E.L.
Southern Medical Journal 93(1): 83-86
2000
ISSN/ISBN: 0038-4348 PMID: 10653076 Document Number: 514026
Methemoglobinemia is an uncommon but important complication associated with the use of topical anesthetics. We describe four cases of methemoglobinemia induced by topical benzocaine use. We review pathophysiology, early diagnosis, and therapy for this reversible yet potentially fatal condition. Physicians who use procedures involving the application of topical anesthetics need to be aware of this side effect to prevent significant morbidity and mortality.